My name is Jacquline Msefula and I have joined the IMPALA study as the Biomedical PhD student. I have a Masters in Health sciences (Antimicrobial Stewardship) obtained from Kamuzu University of Health Sciences, Malawi. My Masters work was on the development and evaluation of the Loop-mediated Isothermal Amplification (LAMP) method in detecting macrolide-resistance in Streptococcus Pneumoniae. I am a Research laboratory technologist by profession, with a focus on Molecular Microbiology, diagnostics development and implementation. My core intellectual and professional goal has always been in the development of effective, user-friendly, reliable scientific tools, methods and knowledge for the past 6 years when I joined the Malawi-Liverpool-Wellcome Trust clinical research programme. My work has covered the evaluation of Streptococcus PCV13 Vaccine and antimicrobial resistance in Children to Monitoring SARS-COVID patterns in Malawi, implementing and improving the laboratory methodology of detection of pathogens and host immunological response. The IMPALA study is offering a platform to boost my career in diagnostics as it has made me a part of assessing the implementation of biomarkers into the predictive algorithm using the Lab-on-a-chip point of care technology (POCT). Molecular methods of POCT is a good platform for resource-limited countries like Malawi, and being a part of improving access to Molecular assays to improve the turnaround time of diagnosis in critically ill children is a great opportunity to make a difference.